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People with Certain Medical Conditions

By CDC.gov

Summary of Recent Changes Revisions were made on December 23, 2020 to reflect recent data supporting increased risk of severe illness among persons with Down syndrome from the virus that causes COVID-19. Revisions also include addition of sickle cell disease and chronic kidney disease to the conditions that might increase the risk of severe illness among children.

We are learning more about COVID-19 every day. The below list of underlying medical conditions is not exhaustive and only includes conditions with sufficient evidence to draw conclusions; it is a living document that may be updated at any time, subject to potentially rapid change as the science evolves. This list is meant to inform clinicians to help them provide the best care possible for patients, and to inform individuals about their level of risk so they can make individual decisions about illness prevention. Notably, the list may not include every condition that might increase one’s risk for developing severe illness from COVID-19, such as those for which evidence may be limited (e.g., rare conditions). Individuals with any underlying medical condition (including those conditions that are NOT on the current list) should consult with their healthcare providers about personal risk factors and circumstances to determine whether extra precautions are warranted.



Adults of any age with certain underlying medical conditions are at increased risk for severe illness from the virus that causes COVID-19. Severe illness from COVID-19 is defined as hospitalization, admission to the ICU, intubation or mechanical ventilation, or death.

Adults of any age with the following conditions are at increased risk of severe illness from the virus that causes COVID-19:

  • Cancer

  • Chronic kidney disease

  • COPD (chronic obstructive pulmonary disease)

  • Down Syndrome

  • Heart conditions, such as heart failure, coronary artery disease, or cardiomyopathies

  • Immunocompromised state (weakened immune system) from solid organ transplant

  • Obesity (body mass index [BMI] of 30 kg/m2 or higher but < 40 kg/m2)

  • Severe Obesity (BMI ≥ 40 kg/m2)

  • Pregnancy

  • Sickle cell disease

  • Smoking

  • Type 2 diabetes mellitus

Read More: Certain Medical Conditions and Risk for Severe COVID-19 Illness | CDC

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